| Date | Player | From | To | Type / Fee |
|---|---|---|---|---|
| Jul 1, 2022 | Matteo Guendouzi |  Arsenal |  Hyeres | Transfer €11M |
| Jul 1, 2022 | Marquinhos |  Sao Paulo | Arsenal | Transfer €3.5M |
| Jul 1, 2022 | Folarin Balogun |  Arsenal Academy | Arsenal | Transfer |
| Jul 1, 2022 | Karl Hein | Arsenal Academy | Arsenal | Transfer |
| Jun 30, 2022 | Ainsley Maitland-Niles |  Roma | Arsenal | End of loan |
| Jun 30, 2022 | Matteo Guendouzi | Hyeres | Arsenal | End of loan |
| Jun 30, 2022 | Konstantinos Mavropanos |  VfB Stuttgart | Arsenal | End of loan |
| Jun 30, 2022 | Lucas Torreira |  Fiorentina | Arsenal | End of loan |
| Jun 30, 2022 | Pablo Mari |  Udinese | Arsenal | End of loan |
| Jun 30, 2022 | Reiss Nelson |  Feyenoord | Arsenal | End of loan |
| Jun 30, 2022 | William Saliba | Hyeres | Arsenal | End of loan |
| Jun 30, 2022 | Hector Bellerin |  Real Betis | Arsenal | End of loan |
| Jun 30, 2022 | Runar Alex Runarsson |  OH Leuven | Arsenal | End of loan |
| Feb 2, 2022 | Dejan Iliev | Arsenal |  Trencin | Free transfer |
| Feb 1, 2022 | Auston Trusty | Arsenal |  Colorado Rapids | Loan |
| Jan 31, 2022 | Auston Trusty | Colorado Rapids | Arsenal | Transfer €1.8M |
| Jan 31, 2022 | Pierre-Emerick Aubameyang | Arsenal |  Barcelona | Free transfer |
| Jan 27, 2022 | Calum Chambers | Arsenal |  Aston Villa | Free transfer |
| Jan 18, 2022 | Sead Kolasinac | Arsenal |  Marseille | Free transfer |
| Dec 31, 2021 | Dejan Iliev |  SKF Sered | Arsenal | End of loan |
| Sep 1, 2021 | David Luiz | Arsenal |  Flamengo | Free transfer |
| Aug 31, 2021 | Takehiro Tomiyasu |  Bologna | Arsenal | Transfer €18.6M |
| Aug 31, 2021 | Reiss Nelson | Arsenal | Feyenoord | Loan |
| Aug 31, 2021 | Hector Bellerin | Arsenal | Real Betis | Loan |
| Aug 31, 2021 | Runar Alex Runarsson | Arsenal | OH Leuven | Loan |
